The Effects of Sinapic Acid on the Development of Metabolic Disorders Induced by Estrogen Deficiency in Rats

Figure 6

Effect of estradiol and sinapic acid on the serum concentration of interleukin 18 (IL-18) in ovariectomized rats. Sinapic acid at doses of 5 mg/kg (SA5) and 25 mg/kg (SA25) or estradiol ((ESTR) 0.2 mg/kg) was administered orally to rats, once daily for 28 days. SHAM: sham-operated control rats; OVX: ovariectomized control rats. Results are presented as the mean ± SEM. One-way ANOVA was used for evaluation of statistical significance of the results. No statistically significant differences were demonstrated in ANOVA.