Research Article
Melatonin Ameliorates the Progression of Atherosclerosis via Mitophagy Activation and NLRP3 Inflammasome Inhibition
Figure 6
Melatonin activated Parkin-mediated mitophagy process through Sirt3-FOXO3a pathway. (a) The acetylation level of forkhead box O3a (FOXO3a) and the expression of Parkin were examined by the Western blot assay. versus the Con group; versus the ox-LDL group; and versus the ox-LDL + MEL group. (b) The expressions of Sirt3, FOXO3a, and Parkin were examined by the Western blot assay. versus the Con group; versus the ox-LDL group; and versus the ox-LDL + MEL group.
(a) |
(b) |