Prophylactic Zinc and Therapeutic Selenium Administration Increases the Antioxidant Enzyme Activity in the Rat Temporoparietal Cortex and Improves Memory after a Transient Hypoxia-Ischemia

Figure 5

Differential effect of the combined treatment with zinc and selenium on chemokine and receptor transcription in the rat hypoxia-ischemia model. (a), (c), and (e) Chemokines levels; (b), (d), (f) receptors of the respective chemokines. CCAO: common carotid artery occlusion for 10 min; Zn + CCAO: chronic zinc administration before CCAO; Zn + CCAO + Se: chronic zinc administration before CCAO followed by selenium administration. The values were normalized against the control group. Each value represents of 5 independent experiments made in triplicate. , one-way ANOVA with post hoc Dunnett’s test when compared to the control untreated group; , Student’s -test when compared with the respective CCAO group.

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