Enhanced Oxidative Damage and Nrf2 Downregulation Contribute to the Aggravation of Periodontitis by Diabetes Mellitus

Table 1

Multiple linear regression analysis between alveolar bone loss, oxidative stress biomarkers, and Nrf2 in diabetic periodontitis and diabetes mellitus groups.

Independent variables	Dependent variable ACJ-AC distance (mm)
	Coef.	Std. err.	value	95% CI
Constant	1.279	0.059	<0.0001	1.135	1.424
3-NT	0.046	0.007	<0.0001	0.030	0.062
4-HNE	0.03	0.006	0.002	0.016	0.045
8-OHdG	0.123	0.029	0.006	0.051	0.194
MDA	0.084	0.014	0.002	0.047	0.121
SOD	−0.877	0.23	0.009	−1.438	−0.315
Nrf2	−0.984	0.399	0.049	−1.959	−0.008

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