Enhanced Oxidative Damage and Nrf2 Downregulation Contribute to the Aggravation of Periodontitis by Diabetes Mellitus

Table 2

Multiple linear regression analysis between apoptosis of periodontium cells, oxidative stress biomarkers, and Nrf2 in diabetic periodontitis and diabetes mellitus groups.

Independent variables	Dependent variable apoptosis of periodontium cells (%)
	Coef.	Std. err.	value	95% CI
Constant	0.103	0.034	0.024	0.019	0.188
3-NT	0.034	0.005	<0.0001	0.023	0.045
4-HNE	0.022	0.004	0.001	0.013	0.032
8-OHdG	0.087	0.023	0.009	0.031	0.143
MDA	0.034	0.006	0.002	0.019	0.05
SOD	−0.618	0.183	0.015	−1.065	−0.17
Nrf2	−0.781	0.265	0.026	−1.429	−0.134

; .