Research Article
Gankyrin Drives Malignant Transformation of Gastric Cancer and Alleviates Oxidative Stress via mTORC1 Activation
Table 2
Association between gankyrin expression and clinicopathological features.
| Clinicopathological features | No. of patients () | Relative gankyrin expression | | | High | Low |
| Age | | | | 0.785 | 0.435 | <45 | 9 | 5 (55.6%) | 4 (44.4%) | | | ≥45 | 68 | 39 (57.4%) | 29 (42.6%) | | | Gender | | | | 1.898 | 0.062 | Male | 52 | 34 (65.4%) | 18 (34.6%) | | | Female | 25 | 11 (44.0%) | 14 (56.0%) | | | Lymph node metastasis | | | | 2.401 | 0.019 | No | 20 | 9 (45.0%) | 11 (55.0%) | | | Yes | 57 | 35 (61.4%) | 22 (38.6%) | | | Distant metastasis | | | | 2.532 | 0.013 | No | 55 | 27 (49.1%) | 28 (50.9%) | | | Yes | 22 | 17 (77.3%) | 5 (22.7%) | | | Pathological grade | | | | 2.557 | 0.084 | I–II | 9 | 7 (77.8%) | 2 (22.2%) | | | III | 62 | 34 (54.8%) | 28 (45.2%) | | | IV | 6 | 3 (50.0%) | 3 (50.0%) | | | Vascular invasion | | | | 2.122 | 0.037 | No | 20 | 9 (45.0%) | 11 (55.0%) | | | Yes | 57 | 35 (61.4%) | 22 (38.6%) | | |
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Patients were divided by high gankyrin staining (H-score ≥ 145) and low gankyrin staining (H-score < 145).
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