Research Article

Gankyrin Drives Malignant Transformation of Gastric Cancer and Alleviates Oxidative Stress via mTORC1 Activation

Table 2

Association between gankyrin expression and clinicopathological features.

Clinicopathological featuresNo. of patients ()Relative gankyrin expression
HighLow

Age0.7850.435
 <4595 (55.6%)4 (44.4%)
 ≥456839 (57.4%)29 (42.6%)
Gender1.8980.062
 Male5234 (65.4%)18 (34.6%)
 Female2511 (44.0%)14 (56.0%)
Lymph node metastasis2.4010.019
 No209 (45.0%)11 (55.0%)
 Yes5735 (61.4%)22 (38.6%)
Distant metastasis2.5320.013
 No5527 (49.1%)28 (50.9%)
 Yes2217 (77.3%)5 (22.7%)
Pathological grade2.5570.084
 I–II97 (77.8%)2 (22.2%)
 III6234 (54.8%)28 (45.2%)
 IV63 (50.0%)3 (50.0%)
Vascular invasion2.1220.037
 No209 (45.0%)11 (55.0%)
 Yes5735 (61.4%)22 (38.6%)

Patients were divided by high gankyrin staining (H-score ≥ 145) and low gankyrin staining (H-score < 145).