Inhibition of HDAC6 Activity Alleviates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats: Potential Role of Peroxiredoxin 1 Acetylation and Redox Regulation

Table 1

General characteristics of each group after 8 weeks.

Parameters/Group	N	D	D + TubA
Blood glucose (mM)	6.27 ± 0.78	28.52 ± 2.95	26.13 ± 3.18
Body weight (g)	479.5 ± 15.31	254.8 ± 19.45	265.4 ± 21.7
Water intake (ml/kg/day)	107.0 ± 7.9	855.0 ± 93.4	826.0 ± 85.4
Food consumption (g/kg/day)	68. 3 ± 5.6	193.9 ± 20.1	187.3 ± 18.5

N: nondiabetic rats; D: STZ-induced diabetic rats; and D + TubA: tubastatin A (10 mg/kg) administered daily by i.p. injection for 1 week in diabetic rats. The results are expressed as the mean ± SEM. versus the N group; .