2,3,5,4-Tetrahydroxystilbene-2-O-beta-D-glucoside Reverses Stress-Induced Depression via Inflammatory and Oxidative Stress Pathways

Figure 2

Effect of THSG on anti-inflammatory properties in the hippocampus and prefrontal cortex. Total TNF-α, NOS-2, IL-1β, and IL-6 mRNAs were isolated from the hippocampal and prefrontal cortex tissues using an mRNA isolation kit. The mRNA expression levels of TNF-α, NOS-2, IL-1β, and IL-6 in the mouse hippocampi are presented in (a, b, c, d). Group (e) shows the mRNA expression levels of TNF-α and IL-6 in mouse prefrontal cortex tissue. Values are expressed as the mean ± SEM (). For statistical significance, and versus the control + Veh group; and versus the CRS + Veh group.

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