Formulated Chinese Medicine Shaoyao Gancao Tang Reduces Tau Aggregation and Exerts Neuroprotection through Anti-Oxidation and Anti-Inflammation

<div>Cytotoxicity and chemical profiles of Bai-Shao, Gan-Cao, and SG-Tang. (a) MTT cell viability assay of HEK-293 and SH-SY5Y cells after treatment with Bai-Shao, Gan-Cao, and SG-Tang (0.1~1000 <i>μ</i>g/ml) for 24 h. To normalize, the relative viability of untreated cells was set as 100%. The red line represents 50% viability. (b) HPLC analysis of Bai-Shao, Gan-Cao, and SG-Tang. Chromatographic patterns (230 and 250 nm) show peaks compatible with paeoniflorin and ammonium glycyrrhizinate. Also shown below are chemical structures of paeoniflorin and ammonium glycyrrhizinate and the relative amounts (in % and mM) of these molecules in Bai-Shao, Gan-Cao, and SG-Tang (0.5 g/ml).</div>

Oxidative Medicine and Cellular Longevity

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Figure 1: Formulated Chinese Medicine Shaoyao Gancao Tang Reduces Tau Aggregation and Exerts Neuroprotection through Anti-Oxidation and Anti-Inflammation 

Figure 1 | Formulated Chinese Medicine Shaoyao Gancao Tang Reduces Tau Aggregation and Exerts Neuroprotection through Anti-Oxidation and Anti-Inflammation 