Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Diaphragm Dysfunction in Rats by Reducing Apoptosis and Inflammation through ROS/MAPK and TLR4/NF-κB Signaling Pathways

Figure 5

Effects of H₂S on the diaphragmatic function and structure of septic rats. (a, b) The body weight and strip weight of rats were measured. (c) The contractile force was measured. (d, e) The maximum tetanic tension and peak twitch tension were detected. (f) The fatigue index was measured. (g, h) The maximal rate of contraction () and the maximal rate of relaxation () were detected. (i) Representative photographs of diaphragm muscle cross-sectional area in diaphragm skeletal muscle myofibers of rats; original magnification, ×400. (j, k) Fast-twitch fibers and slow-twitch fibers were calculated. Values were presented as mean ± SEM (). and compared with the control group; and compared with the LPS group.

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