Oxidative Medicine and Cellular Longevity / 2019 / Article / Fig 3

Research Article

Intracellular Neuroprotective Mechanisms in Neuron-Glial Networks Mediated by Glial Cell Line-Derived Neurotrophic Factor

Figure 3

Mitochondrial functional activity in primary hippocampal cell cultures one day after acute normobaric hypoxia modelling in vitro. (a) The rate of oxygen consumption by mitochondria in the V4 state (glutamate and malate substrates). (b) The rate of oxygen consumption by mitochondria in the V3 state (glutamate and malate substrates, ADP). (c) The rate of oxygen consumption by mitochondria in the V4 state (succinate substrate). (d) The degree of mitochondrial respiratory chain coupling (V3/V4 ratio). The data represent the mean from three independent experiments. Statistical significance was calculated by one-way ANOVA; ; versus “Sham”; #versus “Hypoxia”.
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