L-Cystathionine Protects against Homocysteine-Induced Mitochondria-Dependent Apoptosis of Vascular Endothelial Cells

<div>Effects of L-Cth on Hcy-induced cytotoxicity in HUVECs. (a) Cell viability in HUVECs treated with different concentrations of Hcy was measured by the CCK8 assay. (b) The LDH release from HUVECs treated with different concentrations of Hcy was analyzed. (c) Cell viability in HUVECs treated with 500 <i>μ</i>mol Hcy alone or Hcy plus different concentrations of L-Cth was measured by the CCK8 assay. (d) The LDH release from HUVECs treated with 500 <i>μ</i>mol Hcy alone or Hcy plus different concentrations of L-Cth was analyzed. 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L-Cth: L-cystathionine; LDH: lactate dehydrogenase.</div>

Oxidative Medicine and Cellular Longevity

fig1

Figure 1

Figure 1: L-Cystathionine Protects against Homocysteine-Induced Mitochondria-Dependent Apoptosis of Vascular Endothelial Cells 