L-Cystathionine Protects against Homocysteine-Induced Mitochondria-Dependent Apoptosis of Vascular Endothelial Cells

<div>Effects of L-Cth on apoptosis, caspase-3 activities, and mitochondrial superoxide generation in Hcy-treated HUVECs. (a) HUVEC apoptosis detected by TdT-mediated dUTP nick end labeling (TUNEL) methods (magnification, ×600; scale bar: 20 <i>μ</i>m). (b) Cleavage of caspase-3 analyzed by western blotting. (c) Mitochondrial superoxide generation in HUVECs detected with MitoSOX. 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L-Cth: L-cystathionine.</div>

Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: L-Cystathionine Protects against Homocysteine-Induced Mitochondria-Dependent Apoptosis of Vascular Endothelial Cells 