Effect of Telmisartan in the Oxidative Stress Components Induced by Ischemia Reperfusion in Rats

Figure 6

Modulation of oxidative stress during the I/R lesion. (a) Production of OS during the I/R lesion without telmisartan; overproduction of ROS and RNS overpasses the enzymatic scavenger systems, increasing the damage of the components of the cell such as DNA and proteins. (b) Modulation of OS by telmisartan; producing the increase of SOD and CAT that induces reduction of ROS and RNS.

(a)

(b)