A Solid Dispersion of Quercetin Shows Enhanced Nrf2 Activation and Protective Effects against Oxidative Injury in a Mouse Model of Dry Age-Related Macular Degeneration

Figure 3

Quercetin-SD exerts more potent antioxidant effects in the Nrf2 WT and Nrf2 KO mice models of dry AMD. (a) Determination of ROS levels in serum and retinal tissues. (b) Determination of MDA levels in serum and retinal tissues. (c) Determination of SOD levels in serum and retinal tissues. (d) Determination of GSH-PX levels in serum and retinal tissues. (e) Determination of CAT levels in serum and retinal tissues. Significance: , Nrf2 WT versus Nrf2 KO in the aging control and model control; ^※, ^※※ model control versus aging control; ^#, ^## Q-SD 200 versus model control; ^&, ^&& versus model control; ^@, ^@@ Q-SD 200 versus Q-PC 200 or Q-SD 100 ().

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