Clinical Study

Endothelial Dysfunction in Cystic Fibrosis: Role of Oxidative Stress

Table 1

Participant characteristics, clinical laboratory markers, and pulmonary function in patients with CF and controls.

VariableCFControls value

1818
 Sex (M/F)8/108/10
 Age (y)0.227
 Height (cm)0.337
 Weight (kg)0.868
 BMI (kg/m2)0.225
 Body fat (%)0.902
 SBP (mmHg)0.915
 DBP (mmHg)0.133
 Resting SpO2 (%)0.005
Clinical laboratory markers
 TC (mg/dL)0.009
 HDL (mg/dL)0.002
 LDL (mg/dL)0.508
 Triglycerides (mg/dL)0.144
 Glucose (mg/dL)0.658
 TC : HDL0.075
 hsCRP0.003
Pulmonary function
 FVC (L)0.291
 FEV1 (L)0.025
 FEV1 (% predicted)0.002
 FEV1/FVC (%)<0.001
 FEF25-75 (L/s)<0.001

Values are the . BMI = body mass index; SBP = systolic blood pressure; DBP = diastolic blood pressure; SpO2 = oxygen saturation; TC = total cholesterol; HDL = high-density lipoprotein; LDL = low-density lipoprotein; hsCRP = high-sensitivity C-reactive protein; FVC = forced vital capacity; FEV1 = forced expiratory volume in 1 second; FEF25-75 = forced expiratory flow.