Review Article

Literature-Based Enrichment Insights into Redox Control of Vascular Biology

Table 1

Dictionaries used in DES-RedoxVasc with data source references.

DictionaryEnriched unique terms in the KBStatus

Chemicals/compounds
Chemical Entities of Biological Interest (ChEBI) [84]17981
Toxins (T3DB) [85]2083
Lipids (lipids maps) [86, 87]2852
Amyloids (Human and Mouse); compiled in-house393Newly compiled
Functional annotation
Biological Process (GO) [88]5438
Cellular Component (GO) [88]1125
Molecular Function (GO) [88]1755
Pathways (KEGG [89], Reactome [90], UniPathway [91], and PANTHER [92])1445
Diseases
DOID Ontology (BioPortal)—Human Disease Ontology [93]3467
ADO Ontology (BioPortal)—Alzheimer’s disease ontology [94]937Newly compiled
DMTO Ontology (BioPortal)—Diabetes Mellitus Treatment Ontology [95]1941Newly compiled
HFO Ontology (BioPortal)—Heart Failure Ontology [96]1001Newly compiled
CVDO Ontology (BioPortal)—Cardiovascular Disease Ontology [97]53Newly compiled
HP Ontology (BioPortal)—Human Phenotype Ontology [98]3204
UBERON Ontology (BioPortal)—Uber Anatomy Ontology [99]6540Newly compiled
ICD9 Ontology (BioPortal)—International Classification of Diseases, Version 9 - Clinical Modification [100]688
Drugs
Drugs (DrugBank) [101]3918
ATC Ontology (BioPortal)—Anatomical Therapeutic Chemical Classification [102]1991Newly compiled
CSSO Ontology (BioPortal)—Clinical Signs and Symptoms Ontology210Newly compiled
SIDER (Drug Indications and Side Effects) [103]3190
Human
Human Genes and Proteins (Entrez Gene) [104]21858
Human Transcription Factors [105]1505
Human Transcription Co-Factors (TcoF-DB) [105]384
Human microRNAs (HGNC and Entrez Gene)
PMEDIDs for HGNC and Entrez Gene
1811Updated
Human Long Non-Coding RNAs (HGNC) [106]460
Mutations (tmVar) [107]12514
Human Anatomy (in-house compiled)2538
OMIT Ontology (BioPortal)—Ontology for MicroRNA Target [108]656Newly compiled