Research Article

[Retracted] The Healing of Oxidative Injuries with Trehalose in UVB-Irradiated Rabbit Corneas

Figure 3

Immunohistochemical detection of 8-hydroxyguanosine (8-OhdG) and immunofluorescence of nitrotyrosine (NT) in the UVB-irradiated corneas (daily for 4 days) treated with buffer or 3% or 6% trehalose eye drops. In control corneas, the expression of 8-OhdG (a) and immunofluorescence of NT (e) are practically absent, similarly as after the treatment of UVB-irradiated corneas with drops of 6% trehalose (arrows) (8-OhdG (c), NT (g)). A slightly increased expression of 8-OhdG (arrows) (b) and of NT (f) (arrows) is seen after the treatment with 3% trehalose. The treatment with buffer drops induces the distinct expression (arrows) of 8-OhdG (d) and NT (h) in irradiated corneas. Scale bars: 50 μm.