[Retracted] The Healing of Oxidative Injuries with Trehalose in UVB-Irradiated Rabbit Corneas

Figure 4

Corneal reepithelialization shown by the expression of K3 and K12 in UVB-irradiated corneas of rabbits treated with trehalose drops (3% or 6%) or buffer drops for fourteen days after the end of repeated UVB irradiation. Sections are counterstained with hematoxylin. The individual pictures show the representative images of anti-K3/12-stained control cornea (a) and cornea treated with 3% trehalose (b) or 6% trehalose (c) drops or with buffer drops (d). After the treatment of eyes with trehalose, the corneas were reepithelialized. In contrast, after the treatment with buffer drops, corneas were reepithelialized with the flat epithelium or remain without the epithelium. Scale bars: 50 μm. The quantification of corneal reepithelialization with investigation of K3 genes by real-time-PCR is shown in (e). Each bar represents the from 6 corneas. The values with asterisks are significantly different () from those of buffer-treated corneas.