Verapamil Attenuated Prediabetic Neuropathy in High-Fat Diet-Fed Mice through Inhibiting TXNIP-Mediated Apoptosis and Inflammation

Figure 1

Effects of verapamil treatment on weight, heart rate, and blood pressure of high-fat diet-fed mice. C57/BL6 mice () were fed with normal diet (control) or high-fat diet (HF). HF mice and control mice were treated with verapamil (indicated as HF + VP and VP). The body weight (a), heart ratio (b), diastolic pressure (c), systolic pressure (d), and mean blood pressure (e) of mice were measured at weeks 8, 16, and 34, respectively. Each value represents mean ± SEM (). .

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