Therapeutic Effect of the Mitochondria-Targeted Antioxidant SkQ1 on the Culture Model of Multiple Sclerosis

<div>SkQ1 protects against the LPS-induced decrease in myelin content in oligodendrocytes. (a–d) Representative images of immunostaining for MBP: (a) control and treatment with the reagents (b) SkQ1, (c) LPS, and (d) LPS+SkQ1. (e) MBP staining was quantified, measuring 7-60 fields of view per treatment and expressed as the stained area percentage of untreated control cultures. (f) The number of cells in the field of view. Samples were prepared from the brain of eight newborn rats in seven independent experiments. 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Scale bar, 20 <i>μ</i>m.</div>

Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: Therapeutic Effect of the Mitochondria-Targeted Antioxidant SkQ1 on the Culture Model of Multiple Sclerosis 