Niacin Protects against Butyrate-Induced Apoptosis in Rumen Epithelial Cells

Figure 2

Effects of different concentrations of niacin on the response ratio (RR) of relative cell viability. Rumen epithelial cells were cotreated with 120 mM butyrate and various concentrations niacin for 6 h, and cell viability was determined by MTT assay. Data are presented as the RR. (OD_{(butyrate+niacin)-treated}/OD_{butyrate-treated}), where RR is the response ratio, OD_{butyrate-treated} is the OD value of butyrate-treated cells, OD_{(butyrate+niacin)-treated} is the OD value of cells cotreated with butyrate and niacin, indicates an increase in the relative viability of cells cotreated with butyrate and niacin compared with butyrate-treated cells, and indicates a decrease in the relative viability of cells cotreated with butyrate and niacin compared with butyrate-treated cells. Values with different letters indicate significant differences ().