Mitochondria-Targeted Peptide SS31 Attenuates Renal Tubulointerstitial Injury via Inhibiting Mitochondrial Fission in Diabetic Mice

Table 1

Effect of SS31 on blood glucose, renal function, total cholesterol, and triglyceride and weight of STZ-induced diabetic mice.

Group	n	BW (g)	KW (mg)	KW/BW (mg/g)	BS (mmol/l)	Scr (μmol/l)	BUN (mmol/l)	Proteinuria (μg/ml)	Urine volume (ml)	Proteinuria; (ug/24h)
Control	10
STZ	10^&
STZ+saline	10^&
STZ+SS-31	10^&

Note: BS: blood glucose; BW: body weight; KW: kidney weight of the right kidney; Scr: serum creatinine; BUN: blood urea nitrogen; TC: total cholesterol; TG: triglyceride. ^&3 mice in the STZ group died, 2 mice in the STZ+saline group died, and 3 mice in the STZ+SS31 group died during 24 weeks. , vs. control group; , vs. control group; , vs. STZ group; , vs. STZ group.