Research Article

Testicular Toxicity of Water Pipe Smoke Exposure in Mice and the Effect of Treatment with Nootkatone Thereon

Table 1

Effect of treatment with nootkatone on the urine cotinine level in mice daily exposed to water pipe smoke for 30 days.

GroupCotinine (ng/mL)

AE
WPS
NK

The values in the table are (). Nootkatone (90 mg/kg/day) was given to the mice by oral gavage for 30 days. AE: air exposure; WPS: water pipe smoke; NK: nootkatone. Different superscripts indicate significance as follows ( was considered significant): a denotes significance of the control group vs. different groups, b denotes significance of the WPS group vs. the -treated group, and c denotes significance of the NK group vs. the -treated group.