Research Article
Fine Particulate Matter Leads to Unfolded Protein Response and Shortened Lifespan by Inducing Oxidative Stress in C. elegans
Figure 5
Antioxidant NAC could suppress the UPRmt and UPRER activated by PM2.5. (a) Image of the expression of hsp-6::GFP in SJ4100 (zcIs13 [hsp-6::GFP]) worms and quantification of GFP fluorescence. (b) Image of the expression of hsp-4::GFP in SJ4005 (zcIs4 [hsp-4::GFP] V) worms and quantification of GFP fluorescence. The error bars represent the standard deviation of measurements. The exposure concentration of PM2.5 was 100 mg/L, and 2.5 mM NAC was added simultaneously. vs. control; vs. control; ## vs. PM2.5.
(a) |
(b) |