Research Article

Fine Particulate Matter Leads to Unfolded Protein Response and Shortened Lifespan by Inducing Oxidative Stress in C. elegans

Figure 7

Antioxidant NAC and UPR inhibitor 4-PBA could attenuate the lifespan reduction phenotype caused by PM2.5 in C. elegans. The error bars represent the standard deviation of measurements. The exposure concentration of PM2.5 was 100 mg/L, and NAC and 4-PBA were used at 2.5 mM and 5 mM, respectively. vs. control; vs. control; # vs. PM2.5.
(a)
(b)