p53-Mediated PI3K/AKT/mTOR Pathway Played a Role in Ptox^Dpt-Induced EMT Inhibition in Liver Cancer Cell Lines

Figure 8

Ptox^Dpt inhibited EMT. (a–k) Immunofluorescence analysis of epithelial and mesenchymal markers. (a–d) Control: (a) nuclei in blue; (b) E-cadherin in green; (c) vimentin in red; (d) merge of nuclei, E-cadherin, and vimentin. (e–h) Ptox^Dpt-treated group: (e) nuclei in blue; (f) E-cadherin in green; (g) vimentin in red; (h) merge of nuclei, E-cadherin, and vimentin. Blue arrow: undergoing EMT; white arrow: original or back to the original state. Subject size: (fluorescence), scale bar: 100 μm.

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