Danshenol A Alleviates Hypertension-Induced Cardiac Remodeling by Ameliorating Mitochondrial Dysfunction and Suppressing Reactive Oxygen Species Production

Figure 9

Mechanism of DA ameliorates cardiac remodeling involved in mitochondrial redox signaling pathways in cardiomyocytes. Protein expression of (a, b) p-Ras, Ras, p-Raf, and Raf; (c, d) p-Mek, Mek, p-Erk, and Erk; and (e, f) Ask1, p-Jnk, Jnk, p-p38, and p38 in cardiomyocytes. Results are presented as the (, , and vs. SHR; , , and vs. Ang II; ^### vs. WKY and CON).

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