Research Article

Cerium Oxide Nanoparticles Regulate Insulin Sensitivity and Oxidative Markers in 3T3-L1 Adipocytes and C2C12 Myotubes

Figure 3

Mitochondrial content in RAW 264.7 macrophages (a), 3T3-L1 adipocytes (b), and C2C12 myotubes (c) analyzed with MitoTracker Green assay at 24 h after CeO2 NP treatment at 10, 20, 50, and 100 μg/ml doses in fold change compared to nontreated control (NTC). White shapes: control medium; black shapes: inflammation in macrophages activated with lipopolysaccharide (LPS), adipocytes, and myotubes treated with conditioned medium (CM); , CeO2 NPs vs. control; CeO2 NPs vs. inflammation; data (/group) are expressed as mean (SEM).