Research Article
Cyclophilin A Protects Cardiomyocytes against Hypoxia/Reoxygenation-Induced Apoptosis via the AKT/Nox2 Pathway
Figure 5
The AKT/Nox2 pathway mediates the role of CyPA in opposing hypoxia/reoxygenation-induced apoptosis, whereas inhibiting the AKT/Nox2 pathway partially abrogates CyPA-mediated protection under hypoxia/reoxygenation conditions. The expression of AKT, p-AKT, and Nox2 protein is revealed in representative western blot gel files and summarized data (a–f). vs. the H/R+CyPA group ().
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