The Preventive Effects and the Mechanisms of Action of Navel Orange Peel Hydroethanolic Extract, Naringin, and Naringenin in N-Acetyl-p-aminophenol-Induced Liver Injury in Wistar Rats

Figure 7

Immunohistochemically stained liver sections for Bcl-2 expression detection. (a) Moderate immunohistochemical reaction in normal control. (b) Very low expression in hepatocytes in the liver of APAP-administered rats. (c-e) Moderate, very strong, and strong immunohistochemical reactions for Bcl-2 in the cytoplasm of APAP-administered rats treated with the navel orange peel extract (c), naringin (d), and naringenin (e), respectively (×200).

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