The Preventive Effects and the Mechanisms of Action of Navel Orange Peel Hydroethanolic Extract, Naringin, and Naringenin in N-Acetyl-p-aminophenol-Induced Liver Injury in Wistar Rats

Table 2

Effects of the navel orange peel hydroethanolic extract, naringin, and naringenin on serum ALT, AST, ALP LDH, and GGT activities and albumin and total bilirubin levels in APAP-administered Wistar rats.

Parameter	ALT (U/l)	AST (U/l)	ALP (U/l)	LDH (U/l)	GGT (U/l)	Albumin (g/dl)	Total bilirubin (mg/dl)
Treatments
Normal control
APAP	^a	^a	^a	^a	^a	^a	^a
APAP + navel orange peel extract	^b	^b	^b	^b	^b	^b	^b
APAP + naringin	^b	^b	^b	^b	^b	^b	^b
APAP + naringenin	^b	^b	^b	^b	^b	^b	^b

Data are expressed as of . ^aSignificantly different from the normal value at . ^bSignificantly different from the APAP value at .