Ventilation-Like Mechanical Strain Modulates the Inflammatory Response of BEAS2B Epithelial Cells

Figure 1

Effect of cyclic strain on mitochondrial activity. (a) Representative images of MitoTracker Red-stained control BEAS2B epithelial cells () and cells subjected to sinusoidal (), rectangular (), or triangular cyclic strain () for 4 h. Sites of activated mitochondria (hotspots) are exemplarily designated with white arrowheads. (b) Corresponding counts of mitochondrial hotspots per cell. Box plots indicate median, upper/lower quartile, and bars with minimal/maximal values (or median and range for ). Statistics: analysis of variance (Tukey’s post hoc test). vs. control; vs. rectangular (unless otherwise indicated).

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