Protective Effect of Dinitrosyl Iron Complexes with Glutathione in Red Blood Cell Lysis Induced by Hypochlorous Acid

Figure 2

The effects of glutathione DNIC on HOCl-induced lysis of RBCs. Characteristic kinetic curves of hemolysis initiated by the addition of 0.25 mM HOCl in the absence and in the presence of different concentrations of DNIC (a). Dependence of the rate of RBC lysis on the presence of DNIC (orange) and GSH (green) in the incubation medium (b). The parameters of the HOCl-induced lysis were taken for 100%. .

(a)

(b)