New Insights into Chronological Mobility of Retrotransposons In Vivo

Figure 3

Chronological expression of RTEs (IAP, ERV, L3UTR, L5UTR, LINEs, and SINE B1) in the brain, kidney, lung, liver, heart, and testis. (a) RT-qPCR analysis indicated that all RTEs were significantly upregulated in the aged mouse brain. (b) RT-qPCR analysis of RTEs showing that they were significantly upregulated in aged mouse kidneys. (c) RT-qPCR analysis showed that the RTE expression was significantly downregulated in aged mouse lungs. (d) RT-qPCR analysis of RTEs in the heart showed that only IAP was upregulated, while L3UTR, LINEs, and SINE B1 were downregulated. (e) RT-qPCR analysis of liver RTEs showed that the majority of them were significantly decreased with age. (f) RT-qPCR analysis of RTEs in the testis showed that the majority of them were significantly decreased in aged testes (24 months of age). , , and .

(a) Brain

(b) Kidney

(c) Lungs

(d) Heart

(e) Liver

(f) Testis