Phosphatidylcholine Extends Lifespan via DAF-16 and Reduces Amyloid-Beta-Induced Toxicity in Caenorhabditis elegans

Table 3

Effect of phosphatidylcholine on Aβ-induced toxicity in C. elegans.

	PC (mg/l)	Time when 50% of worms were paralyzed (h)	value^1	% effect^2
1st experiment	0	4.1
	10	6.3	<0.001	55.7
	100	7.0	<0.001	71.3
2nd experiment	0	4.1
	10	7.1	<0.001	71.8
	100	7.4	<0.001	77.8
3rd experiment	0	3.3
	10	6.7	<0.001	106.1
	100	8.4	<0.001	157.7

value was calculated using the log-rank test by comparing the rate of paralysis in the untreated control group (0 mg/l phosphatidylcholine) to that in the phosphatidylcholine-treated group (10 or 100 mg/l phosphatidylcholine). ²% effects were calculated by , where is the time when 50% of worms were paralyzed in the phosphatidylcholine-treated group and is the time when 50% of worms were paralyzed in the untreated control group. PC: phosphatidylcholine.