Phosphatidylcholine Extends Lifespan via DAF-16 and Reduces Amyloid-Beta-Induced Toxicity in Caenorhabditis elegans

Table 4

Effect of phosphatidylcholine on lifespan of wild-type N2 and long-lived mutants.

		Mean lifespan (day)		value^1	% effect^2
		Control	100 mg/l PC
N2	1st experiment	17.5	20.6	<0.001	17.6
	2nd experiment	21.6	24.9	<0.001	15.4
age-1 (hx546)	1st experiment	29.2	28.9	0.970	-1.0
	2nd experiment	33.8	30.4	0.090	-10.1
clk-1 (e2519)	1st experiment	22.2	25.4	0.013	14.7
	2nd experiment	22.0	25.8	<0.001	17.2
eat-2 (ad465)	1st experiment	21.9	25.8	0.001	18.3
	2nd experiment	23.7	27.4	0.002	15.6

value was calculated using the log-rank test by comparing the survival of the untreated control group to that of the phosphatidylcholine-treated group. ²% effects were calculated by , where is the mean lifespan of the phosphatidylcholine-treated group and is the mean lifespan of the untreated control group. PC: phosphatidylcholine.