Research Article

Phosphatidylcholine Extends Lifespan via DAF-16 and Reduces Amyloid-Beta-Induced Toxicity in Caenorhabditis elegans

Table 5

Effect of daf-16 knockdown on lifespan extension with phosphatidylcholine.

RNAiMean lifespan (day) value1
Control100 mg/l PC

1st experimentEV17.921.1<0.001
daf-1615.515.60.622
2nd experimentEV18.520.20.005
daf-1615.716.40.255

value was calculated using the log-rank test by comparing the survival rate of the untreated control group to that of the phosphatidylcholine-treated group. PC: phosphatidylcholine; EV: empty vector.