New C-Terminal Conserved Regions of Tafazzin, a Catalyst of Cardiolipin Remodeling

Figure 7

Secondary structure of tafazzin. Helices and extended regions predicted by JPred4 are marked green and blue, respectively. Mouse, CT; walrus, seal, bear, orca, bat, and rhino, T2; beaver, rabbit, and NMR, shortened UT where underlined regions support their assignment to UT (beaver and NMR also have different isoforms listed in Table S1). Abbreviations: mouse: NP_852657.1, isoform 2 (Mus musculus); walrus: XP_004414556.1, X1 (Odobenus rosmarus); seal: XP_006739411.1, X1 (Leptonychotes weddellii); orca: XP_012394911.1, X1 (Orcinus orca); bear: XP_026344949.1, X1 (Ursus arctos); bat: XP_015979168.1, X1 (Rousettus aegyptiacus); rhino: XP_014653014.1, X1 (Ceratotherium simum); beaver: XP_020040765.1, X1 (Castor canadensis); rabbit: XP_017194047.1, X1 (Oryctolagus cuniculus); NMR: XP_004875054.1, X1 (Heterocephalus glaber). Entirely conserved positions are labeled with asterisks.