Unraveling the Potential Role of Glutathione in Multiple Forms of Cell Death in Cancer Therapy

<div>The antioxidant role of cellular GSH. Glutathione peroxidase (GPX) converts H<sub>2</sub>O<sub>2</sub> and Lipid-OOH to H<sub>2</sub>O and Lipid-OH where GSH is oxidized to GSSG, and glutathione reductase (GR) reduced GSSG to GSH dependent on NADPH, thereby forming a redox cycle to prevent oxidative damage.</div>

Oxidative Medicine and Cellular Longevity

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Figure 5

Figure 5: Unraveling the Potential Role of Glutathione in Multiple Forms of Cell Death in Cancer Therapy 