Research Article

Carvacrol and Thymol Modulate the Cross-Talk between TNF-α and IGF-1 Signaling in Radiotherapy-Induced Ovarian Failure

Table 1

Effect of CAR or thymol (80 mg/kg IP; once daily for 5 days, respectively) on ovarian weight, relative ovary weight, and total antioxidant capacity in rats subjected to a single dose of whole-body irradiation (3.2 Gy).

Treated groupsOvarian weight (mg)Relative ovary wt (mg/100 g body weight)TAC (μM/l)

Control
IR
IR/CAR
IR/thymol

Data expressed as (). a,bSignificantly different from the control or radiation group, respectively, at using one-way ANOVA followed by the Tukey-Kramer as a post hoc test. IR: irradiation; IR/CAR: irradiation/carvacrol; CAR: carvacrol; TAC: total antioxidant capacity.