Simvastatin Reduces Hepatic Oxidative Stress and Endoplasmic Reticulum Stress in Nonalcoholic Steatohepatitis Experimental Model
Effect of a MCD diet and treatment with simvastatin on GRP78 and ATF6 protein by Western blot analysis. The data are expressed as the (S.D.). # versus CO+V, SIM 4, and NASH+V. versus CO+V, SIM 4, and NASH+V. CO+V: control plus vehicle; SIM 4: control plus simvastatin 4 mg/kg; NASH+V: NASH plus vehicle; NASH+SIM 4: NASH plus simvastatin 4 mg/kg.