Research Article

Bailcalin Protects against Diabetic Cardiomyopathy through Keap1/Nrf2/AMPK-Mediated Antioxidative and Lipid-Lowering Effects

Figure 3

BAI improved T2DM-induced cardiac dysfunction. Parameters of cardiac functions examined by echocardiography: (a) heart rate (HR), (b) left ventricle (LV) end-diastolic diameter (LVEDd), (c) LV end-systolic diameter (LVEDs), (d) LV end-diastolic volume (LVVd), (e) LV end-systolic volume (LVVs), (f) LV ejection fraction (EF), and (g) LV fractional shortening (FS); parameters examined by pressure-volume loop: (h) dp/dt, (i) -dp/dt, and (j) Tau. in the VEH and BAI groups; in the DM and DM+BAI groups. VEH: vehicle; DM: diabetes mellitus; BAI: Bailcalin. compared with the VEH or BAI group; # compared with the DM group.