The Role of Traditional Chinese Medicine in the Regulation of Oxidative Stress in Treating Coronary Heart Disease

Figure 1

The mechanism of TCM in preventing CHD by oxidative stress-related signaling pathways. HJT: Hongjingtian injection; mTOR: mammalian target of rapamycin; LC-3B: light chain 3B; NADPH: nicotinamide adenine dinucleotide phosphate; GSSG: glutathione disulfide; GSH: glutathione; SOD: superoxide dismutase; PI3K: phosphoinositide 3-kinase; Akt: serine/threonine kinase; Nrf2: nuclear factor erythroid-2-related factor 2; AMPK: adenosine monophosphate-activated protein kinase; PUN: punicalagin; DSS: Danshensu; OP-D: Ophiopogonin D; TXL: Tongxinluo; TNF-α: tumor necrosis factor-α; IL-6: interleukin-6; NF-κB: nuclear factor-κB; IL-10: interleukin-10; CRP: C-reaction protein; DG: Dunye Guanxinning; TMYX: Tongmai Yangxin pill; DSY: Dan-Shen-Yin; OSR: oxysophoridine; QSYQ: Qi-shen-yi-qi; XO: xanthine oxidase; NOX: NADPH oxidase; eNOS: endothelial nitric oxide synthase; CP: cardiotonic pill; SXSM: Shenxian-shengmai; SMS: Shengmai San; Bcl-2: B-cell lymphoma-2; Bax: Bcl-2-associated protein X; YQFM: YiQiFuMai powder injection; SAL: salvianolic acid; TAN: tanshinone; GXT: Guanxintai; BXT: Bao-Xin-Tang; G. acuta: Gentianella acuta.