|
| Type of TCM | TCM (molecular formula) | Type of study | Mechanism of action | References |
|
| The bioactive ingredients of TCM | SAL (C36H30O16; C26H22O10),
TAN (C18H12O3; C19H18O3) | In vivo | Downregulation of factors participated in oxidative stress and apoptosis; inhibition of intracellular calcium and cell adhesion pathways | Wang et al. [129] |
| Danshensu (C9H10O5) | In vivo | Activation of the Akt/ERK1/2/Nrf2 signaling pathway | Yu et al. [35] |
| Astragalin (C21H20O11) | In vivo | Antiapoptotic, antioxidative, and anti-inflammatory activities | Qu et al. [41] |
| OP-D (C44H70O16) | | | |
| Curcumin (C21H20O6) | In vivo | Activating JAK2/STAT3 signal pathway, reducing oxidative damage and suppressing myocardium apoptosis | Liu et al. [111] |
| Punicalagin (C48H28O30) | In vivo | Activation of AMPK | Ding et al. [60] |
| Barbaloin (C21H22O9) | In vivo | Antioxidative, anti-inflammatory | Zhang et al. [93] |
| OSR (C15H24N2O2) | In vivo | Antiapoptotic, anti-inflammatory, and antioxidative | Meng et al. [68] |
| G. acuta (C13H8O2) | In vivo | Activities of antioxidative and antiapoptosis | Wang et al. [81] |
| Azafrin (C27H38O4) | In vivo, in vitro | Activation of the Nrf2-ARE pathway | Yang et al. [158] |
|
| Traditional Chinese medicine decoction | Bao-Xin-Tang | In vivo | Antioxidant and anti-inflammation properties | Wang et al. [81] |
| Dan-Shen-Yin | In vivo | Anti-inflammatory and antioxidant properties | Yan et al. [86] |
|
| Patented drugs from traditional Chinese medicine | Dunye Guanxinning | In vivo | Inhibits inflammasome activity through the AMPK pathway | Zhang et al. [91] |
| Hongjingtian injection | In vivo, in vitro | Decreasing myocardial oxidative damage | Zhang et al. [93] |
| Guanxintai | In vivo, in vitro | Reduced NOX and MAPK proteins | Yang et al. [158] |
| Cardiotonic pill | In vivo | Inhibiting NOX activity | Yang et al. [105] |
| Shenxian-shengmai | In vivo | Enhanced the activity of SOD and aggrandized the content of GSH | Zhao et al. [110] |
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