Long-Term Moderate Exercise Combined with Metformin Treatment Induces an Hormetic Response That Prevents Strength and Muscle Mass Loss in Old Female Wistar Rats

Figure 3

Grip strength. Grip strength was determined by dynamometry as described in Materials and Methods. The measurements are expressed in Newton per kilogram of rat weight. The data represented are the mean of 3 determinations in 5 different rats for each experimental group. The curve was adjusted by means of a polynomial regression. Comparisons were made in the different ages and treatments with respect to the sedentary rats (); the exact probability value is indicated in the graph. The comparisons were established by a multivariate test and corroborated with a Student -test.