Astrocyte-Targeted Transporter-Utilizing Derivatives of Ferulic Acid Can Have Multifunctional Effects Ameliorating Inflammation and Oxidative Stress in the Brain

Figure 7

A schematic presentation of the effects of FA-derivatives 1-3 on biological markers that can decrease the levels of Aβ in astrocytes in AD. Aβ: β-amyloid; AChE: acetylcholine esterase; BACE1: β-site amyloid precursor protein (APP) cleaving enzyme 1; COX: cyclooxygenases; LOX: lipoxygenases; mTOR: mammalian (or mechanistic) target for rapamycin (mTOR); NF-κB: transcription factor NF-κB.