Astrocyte-Targeted Transporter-Utilizing Derivatives of Ferulic Acid Can Have Multifunctional Effects Ameliorating Inflammation and Oxidative Stress in the Brain

Table 1

Ability of ferulic acid (FA) and its derivatives 1-3 to bind to LAT1 in mouse primary astrocytes presented as half maximal inhibitory concentrations (IC₅₀ values) of LAT1-probe substrate, [¹⁴C]-L-leucine uptake. Data are presented as the ; -4.

Compound	IC50 in astrocytes (μM)
FA-derivative 1
FA-derivative 2
FA-derivative 3
FA	No inhibition