Research Article
Bloom Syndrome Protein Activates AKT and PRAS40 in Prostate Cancer Cells
Table 1
DEPs involved in the regulation of protein phosphorylation (GO: 0001932).
| Accession | UniProtKB | Gene | Cancer/normal | Cancer/normal | Cancer/BPH | Cancer/BPH | Number | AC | Name | 118, 119, 121/113, 114 | value | 118, 119, 121/115, 116, 117 | value |
| Upregulated proteinsa | | | | | | | Q9Y4K3 | Q9Y4K3 | TRAF6 | 1.470 | 0.002 | 1.246 | 0.004 | Q96B36 | Q96B36 | AKT1S1 | 1.212 | 0.006 | 1.218 | 0.001 | Q8TB45 | Q8TB45 | DEPTOR | 1.446 | 0.002 | 1.221 | 0.002 | Q59FU8 | P25445 | FAS | 1.606 | 0.013 | 1.239 | 0.020 | Q02750 | Q02750 | MAP2K1 | 1.225 | 0.004 | 1.227 | 0.000 | P54132 | P54132 | BLM | 1.258 | 0.001 | 1.215 | 0.001 | P31749 | P31749 | AKT1 | 1.207 | 0.010 | 1.205 | 0.001 | Downregulated proteinsb | | | | | | | A0A1V1FWL6 | P49815 | TSC2 | 0.706 | 0.001 | 0.786 | 0.002 | A0A024R593 | Q15173 | PPP2R5B | 0.719 | 0.002 | 0.777 | 0.004 |
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aProteins with fold ( ) are considered upregulated. bProteins with fold ( ) are considered downregulated. |