RNA Expression Profile and Alternative Splicing Signatures of Genistein-Treated Breeder Hens Revealed by Hepatic Transcriptomic Analysis

Figure 2

Effects of 400 mg/kg dietary genistein supplementation of LBB hens on differential gene expression and functional enrichment. (a) Number of differentially expressed genes (DEGs) (up/downregulated) in LBB hens after genistein supplementation at 40 mg/kg. (b) Significantly enriched biological processes. (c) Number of DEGs enriched in GOs and pathways. (d) Enriched biological processes of level 6 were shown. (e) Protein-protein interaction analysis using DEGs of the CON vs. LGE groups. Circular nodes represent genes/proteins; rectangles represent KEGG pathways or GO biological process terms. The pathways are colored with a gradient from yellow to blue, in which yellow indicates a smaller value and blue indicates a larger value. GO biological processes are colored red. In the fold change analysis, genes/proteins are colored red for upregulation or green for downregulation.

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